Anemia of Inflammation or Chronic Disease

What is anemia of inflammation? Anemia of inflammation, also called anemia of chronic disease or ACD, is a type of anemia that affects people who have conditions that cause inflammation, such as infections, autoimmune diseases, cancer , and chronic kidney disease (CKD). Anemia is a condition in which your blood has fewer red blood cells than normal. Your red blood cells…

Sickle Cell Trait & Other Hemoglobinopathies & Diabetes (For Providers)

The hemoglobin A1C (A1C) test can be unreliable for diagnosing or monitoring diabetes and prediabetes in people with inherited hemoglobin variants, also called hemoglobinopathies. Hemoglobins S and E are prevalent variants in people of African, Mediterranean, or Southeast Asian descent. These variants interfere with some A1C tests—both laboratory and point-of-care tests. If A1C tests are…

Celiac Disease Testing (for Health Care Professionals)

Serologic tests for celiac disease provide an effective first step in identifying candidates for intestinal biopsy. If serologic or genetic tests indicate the possibility of celiac disease, a biopsy should be done promptly and before initiating any dietary changes.  Genetic tests that confirm the presence or absence of specific genes associated with celiac disease may…

Aplastic Anemia & Myelodysplastic Syndromes

What are aplastic anemia and myelodysplastic syndromes (MDS)? Aplastic anemia and myelodysplastic syndromes (MDS) are rare and serious disorders that affect the bone marrow and blood. Bone marrow is the soft, spongelike tissue inside the bones. Bone marrow makes stem cells that develop into one of the three types of blood cells—red blood cells, white…